A polypeptide member of the transforming growth factor beta superfamily of cytokines
tgf-b1
TLR9-dependent recognition of MCMV by IPC and DC generates coordinated cytokine responses that activate antiviral NK cell perform Pure interferon-producing cells (IPC) reply to viruses by secreting sort I interferon (IFN) and interleukin-12 (IL-12). Toll-like receptor…Continue Reading
tgf-b1
Adipocyte-derived Th2 cytokines and myeloid PPARdelta regulate macrophage polarization and insulin sensitivity. The polarization of adipose tissue-resident macrophages towards the alternatively activated, anti-inflammatory M2 phenotype is believed to enhance insulin sensitivity. Nevertheless, the mechanisms controlling tissue…Continue Reading
tgf-b1
Mitochondrial reactive oxygen species promote manufacturing of proinflammatory cytokines and are elevated in TNFR1-associated periodic syndrome (TRAPS). Reactive oxygen species (ROS) have a longtime function in irritation and host protection, as they kill intracellular micro organism…Continue Reading
