A polypeptide member of the transforming growth factor beta superfamily of cytokines

Human Dedicator Of Cytokinesis Protein

Human Dedicator Of Cytokinesis Protein

tgf-b1

 

Dedicator of cytokinesis 2, a novel regulator for clean muscle phenotypic modulation and vascular transforming.

 

BACKGROUND

 

Vascular clean muscle cell (SMC) phenotypic modulation and vascular transforming contribute to the event of a number of vascular issues corresponding to restenosis after angioplasty, transplant vasculopathy, and atherosclerosis. The mechanisms underlying these processes, nonetheless, stay largely unknown.

OBJECTIVE

The target of this examine is to find out the function of dedicator of cytokinesis 2 (DOCK2) in SMC phenotypic modulation and vascular transforming.

RESULTS

Platelet-derived progress factor-BB induced DOCK2 expression whereas modulating SMC phenotype. DOCK2 deficiency diminishes platelet-derived progress factor-BB or serum-induced downregulation of SMC markers. Conversely, DOCK2 overexpression inhibits SMC marker expression in main cultured SMC.

Mechanistically, DOCK2 inhibits myocardin expression, blocks serum response issue nuclear location, attenuates myocardin binding to serum response issue, and thus attenuates myocardin-induced clean muscle marker promoter exercise.

Furthermore, DOCK2 and Kruppel-like issue Four cooperatively inhibit myocardin-serum response issue interplay. In a rat carotid artery balloon-injury mannequin, DOCK2 is induced in media layer SMC initially and neointima SMC subsequently after vascular damage.

The knockdown of DOCK2 dramatically inhibits the neointima formation by 60%. Most significantly, knockout of DOCK2 in mice markedly blocks ligation-induced intimal hyperplasia whereas restoring SMC contractile protein expression.

CONCLUSIONS

Our research recognized DOCK2 as a novel regulator for SMC phenotypic modulation and vascular lesion formation after vascular damage. Subsequently, concentrating on DOCK2 could also be a possible therapeutic technique for the prevention of vascular transforming in proliferative vascular ailments.

tgf-b1
tgf-b1

Dedicator of Cytokinesis 1 (DOCK1) Antibody

Engulfment and cell motility 1/dedicator of cytokinesis 180 (Elmo1/Dock180) is a bipartite guanine nucleotide change issue for the monomeric GTPase Ras-related C3 botulinum toxin substrate 1 (Rac1). Elmo1/Dock180 regulates Rac1 exercise in a particular spatiotemporal method in endothelial cells (ECs) throughout zebrafish growth and acts downstream of the Netrin-1/Unc5-homolog B (Unc5B) signaling cascade.

 

  • Nonetheless, mechanistic particulars on the pathways by which Elmo1/Dock180 regulates endothelial operate and vascular growth remained elusive. On this examine, we aimed to research the vascular operate of Elmo1 and Dock180 in human ECs and through vascular growth in zebrafish embryos.
  • In vitro overexpression of Elmo1 and Dock180 in ECs diminished caspase-3/7 exercise and annexin V-positive cell quantity upon induction of apoptosis. This protecting impact of Elmo1 and Dock180 is mediated by activation of Rac1, p21-activated kinase (PAK) and AKT/protein kinase B (AKT) signaling.
  • In zebrafish, Elmo1 and Dock180 overexpression diminished the entire apoptotic cell and apoptotic EC quantity and promoted the formation of blood vessels throughout embryogenesis. In conclusion, Elmo1 and Dock180 defend ECs from apoptosis by the activation of the Rac1/PAK/AKT signaling cascade in vitro and in vivo.
  • Thus, Elmo1 and Dock180 facilitate blood vessel formation by stabilization of the endothelium throughout angiogenesis.

 

Dedicator Of Cytokinesis 1 (DOCK1) Polyclonal Antibody (Human), APC

BACKGROUND
Dedicator of cytokinesis 8 (DOCK8) deficiency is typified by recurrent infections, elevated serum IgE ranges, eosinophilia, and a excessive incidence of allergic and autoimmune manifestations.
OBJECTIVE
We sought to find out the function of DOCK8 within the institution and upkeep of human B-cell tolerance.
METHODS

Autoantibodies had been measured within the plasma of DOCK8-deficient sufferers. The antibody-coding genes from new emigrant/transitional and mature naive B cells had been cloned and assessed for his or her capability to bind self-antigens.

Regulatory T (Treg) cells within the blood had been analyzed via circulation cytometry, and their operate was examined by analyzing their capability to inhibit the proliferation of CD4(+)CD25(-) effector T cells.

RESULTS
DOCK8-deficient sufferers had elevated ranges of autoantibodies of their plasma. We decided that central B-cell tolerance didn’t require DOCK8, as evidenced by the usually low frequency of polyreactive new emigrant/transitional B cells in DOCK8-deficient sufferers. In distinction, autoreactive B cells had been enriched within the mature naive B-cell compartment, revealing a faulty peripheral B-cell tolerance checkpoint.
As well as, we discovered that Treg cells had been decreased and exhibited impaired suppressive exercise in DOCK8-deficient sufferers.
CONCLUSIONS
Our information help a vital function for DOCK8 in Treg cell homeostasis and performance and the enforcement of peripheral B-cell tolerance.

Dedicator Of Cytokinesis 1 (DOCK1) Antibody

abx330938-100ul 100 ul
EUR 425

Dedicator Of Cytokinesis 1 (DOCK1) Antibody

20-abx325559
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug

Dedicator Of Cytokinesis 1 (DOCK1) Antibody

20-abx333995
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Recombinant Dedicator Of Cytokinesis 1 (DOCK1)

4-RPG175Hu01
  • EUR 467.36
  • EUR 228.00
  • EUR 1477.60
  • EUR 559.20
  • EUR 1018.40
  • EUR 376.00
  • EUR 3544.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Dedicator Of Cytokinesis 1 expressed in: E.coli

Dedicator Of Cytokinesis 1 (DOCK1) Antibody (HRP)

20-abx335295
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Dedicator Of Cytokinesis 1 (DOCK1) Antibody (FITC)

20-abx335296
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Dedicator Of Cytokinesis 1 (DOCK1) Antibody (Biotin)

20-abx335297
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Human Dedicator Of Cytokinesis 1 (DOCK1) Protein

20-abx066282
  • EUR 648.00
  • EUR 272.00
  • EUR 1998.00
  • EUR 773.00
  • EUR 467.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Dedicator Of Cytokinesis 1 (DOCK1) Polyclonal Antibody (Human)

4-PAG175Hu01
  • EUR 247.00
  • EUR 2510.00
  • EUR 625.00
  • EUR 310.00
  • EUR 214.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Dedicator Of Cytokinesis 1 (DOCK1)

Dedicator Of Cytokinesis 1 (DOCK1) Polyclonal Antibody (Human), APC

4-PAG175Hu01-APC
  • EUR 345.00
  • EUR 3275.00
  • EUR 912.00
  • EUR 440.00
  • EUR 219.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Dedicator Of Cytokinesis 1 (DOCK1). This antibody is labeled with APC.

Dedicator Of Cytokinesis 1 (DOCK1) Polyclonal Antibody (Human), Biotinylated

4-PAG175Hu01-Biotin
  • EUR 311.00
  • EUR 2460.00
  • EUR 727.00
  • EUR 381.00
  • EUR 219.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Dedicator Of Cytokinesis 1 (DOCK1). This antibody is labeled with Biotin.

Dedicator Of Cytokinesis 1 (DOCK1) Polyclonal Antibody (Human), Cy3

4-PAG175Hu01-Cy3
  • EUR 419.00
  • EUR 4325.00
  • EUR 1175.00
  • EUR 545.00
  • EUR 251.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Dedicator Of Cytokinesis 1 (DOCK1). This antibody is labeled with Cy3.

Dedicator Of Cytokinesis 1 (DOCK1) Polyclonal Antibody (Human), FITC

4-PAG175Hu01-FITC
  • EUR 296.00
  • EUR 2640.00
  • EUR 750.00
  • EUR 372.00
  • EUR 195.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Dedicator Of Cytokinesis 1 (DOCK1). This antibody is labeled with FITC.

Dedicator Of Cytokinesis 1 (DOCK1) Polyclonal Antibody (Human), HRP

4-PAG175Hu01-HRP
  • EUR 316.00
  • EUR 2855.00
  • EUR 807.00
  • EUR 398.00
  • EUR 206.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Dedicator Of Cytokinesis 1 (DOCK1). This antibody is labeled with HRP.

Dedicator Of Cytokinesis 1 (DOCK1) Polyclonal Antibody (Human), PE

4-PAG175Hu01-PE
  • EUR 296.00
  • EUR 2640.00
  • EUR 750.00
  • EUR 372.00
  • EUR 195.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Dedicator Of Cytokinesis 1 (DOCK1). This antibody is labeled with PE.

Human Dedicator Of Cytokinesis Protein 1 (DOCK1) ELISA Kit

abx259546-96tests 96 tests
EUR 911

Mouse Dedicator of cytokinesis protein 1, Dock1 ELISA KIT

ELI-47076m 96 Tests
EUR 865

Human Dedicator of cytokinesis protein 1, DOCK1 ELISA KIT

ELI-09218h 96 Tests
EUR 824

Dedicator Of Cytokinesis 1 (DOCK1) Polyclonal Antibody (Human), APC-Cy7

4-PAG175Hu01-APC-Cy7
  • EUR 571.00
  • EUR 6430.00
  • EUR 1705.00
  • EUR 760.00
  • EUR 319.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Dedicator Of Cytokinesis 1 (DOCK1). This antibody is labeled with APC-Cy7.

Dedicator of Cytokinesis 2 (DOCK2) Antibody

20-abx149900
  • EUR 425.00
  • EUR 342.00
  • 100 ug
  • 50 ug

Dedicator of Cytokinesis 2 (DOCK2) Antibody

20-abx129016
  • EUR 425.00
  • EUR 133.00
  • EUR 1205.00
  • EUR 578.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Dedicator of Cytokinesis 4 (DOCK4) Antibody

20-abx129252
  • EUR 425.00
  • EUR 133.00
  • EUR 1205.00
  • EUR 578.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Dedicator of Cytokinesis 2 (DOCK2) Antibody

20-abx126888
  • EUR 411.00
  • EUR 592.00
  • 100 ul
  • 200 ul

Dedicator of Cytokinesis 2 (DOCK2) Antibody

20-abx112010
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul

Dedicator of Cytokinesis 3 (DOCK3) Antibody

20-abx112011
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul

Dedicator Of Cytokinesis 3 (DOCK3) Antibody

20-abx172052
  • EUR 857.00
  • EUR 439.00
  • 1 mg
  • 200 ug

Dedicator Of Cytokinesis 4 (DOCK4) Antibody

20-abx172053
  • EUR 857.00
  • EUR 439.00
  • 1 mg
  • 200 ug

Dedicator of Cytokinesis 3 (DOCK3) Antibody

20-abx313603
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Dedicator Of Cytokinesis 3 (DOCK3) Antibody

20-abx176110
  • EUR 1205.00
  • EUR 578.00
  • 1 mg
  • 200 ug

Dedicator Of Cytokinesis 2 (DOCK2) Antibody

20-abx326569
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug

Recombinant Dedicator Of Cytokinesis 2 (DOCK2)

4-RPG182Hu01
  • EUR 458.40
  • EUR 226.00
  • EUR 1444.00
  • EUR 548.00
  • EUR 996.00
  • EUR 370.00
  • EUR 3460.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Dedicator Of Cytokinesis 2 expressed in: E.coli

Recombinant Dedicator Of Cytokinesis 4 (DOCK4)

4-RPG184Hu01
  • EUR 467.36
  • EUR 228.00
  • EUR 1477.60
  • EUR 559.20
  • EUR 1018.40
  • EUR 376.00
  • EUR 3544.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Dedicator Of Cytokinesis 4 expressed in: E.coli

Dedicator of Cytokinesis Protein 10 (DOCK10) Antibody

20-abx301562
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Dedicator of Cytokinesis Protein 5 (DOCK5) Antibody

abx122686-100ug 100 ug
EUR 391

Dedicator of Cytokinesis Protein 11 (DOCK11) Antibody

20-abx007957
  • EUR 300.00
  • EUR 439.00
  • EUR 189.00
  • 100 ul
  • 200 ul
  • 30 ul

Dedicator of Cytokinesis Protein 5 (DOCK5) Antibody

20-abx311377
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Dedicator of Cytokinesis 3 (DOCK3) Antibody (HRP)

20-abx313604
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Dedicator of Cytokinesis 3 (DOCK3) Antibody (FITC)

20-abx313605
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Dedicator of Cytokinesis 3 (DOCK3) Antibody (Biotin)

20-abx313606
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Dedicator of Cytokinesis Protein 11 (DOCK11) Antibody

20-abx219454
  • EUR 425.00
  • EUR 342.00
  • 100 ug
  • 50 ug

Dedicator of Cytokinesis Protein 10 (DOCK10) Antibody

abx145342-100ug 100 ug
EUR 391

Human Dedicator Of Cytokinesis 4 (DOCK4) Protein

20-abx168105
  • EUR 648.00
  • EUR 272.00
  • EUR 1998.00
  • EUR 773.00
  • EUR 467.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Human Dedicator Of Cytokinesis 2 (DOCK2) Protein

20-abx166509
  • EUR 648.00
  • EUR 272.00
  • EUR 1943.00
  • EUR 759.00
  • EUR 467.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Human Dedicator Of Cytokinesis 3 (DOCK3) Protein

20-abx653130
  • EUR 578.00
  • EUR 258.00
  • EUR 1720.00
  • EUR 690.00
  • EUR 425.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Mouse Dedicator of cytokinesis protein 8 (Dock8)

1-CSB-EP807451MO
  • EUR 505.00
  • EUR 265.00
  • EUR 1827.00
  • EUR 766.00
  • EUR 1218.00
  • EUR 335.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Mouse Dedicator of cytokinesis protein 8(Dock8),partial expressed in E.coli

Mouse Dedicator of cytokinesis protein 8 (Dock8)

1-CSB-EP807451MO1
  • EUR 505.00
  • EUR 265.00
  • EUR 1827.00
  • EUR 766.00
  • EUR 1218.00
  • EUR 335.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Mouse Dedicator of cytokinesis protein 8(Dock8),partial expressed in E.coli

Mouse Dedicator of cytokinesis protein 8 (Dock8)

1-CSB-YP807451MO1
  • EUR 586.00
  • EUR 299.00
  • EUR 2172.00
  • EUR 900.00
  • EUR 1442.00
  • EUR 382.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Mouse Dedicator of cytokinesis protein 8(Dock8),partial expressed in Yeast

Human Dedicator Of Cytokinesis Protein 1 (DOCK1) ELISA Package

Dedicator of cytokinesis 8 (DOCK8) deficiency is an autosomal recessive sort of mixed immunodeficiency with elevated IgE.
On this report, we describe a Japanese woman of non-consanguineous household affected by acute eosinophilic pneumonia (AEP) as a presenting function of DOCK8 deficiency.

Though AEP was self-limiting, consecutively skilled recurrent respiratory infections, extreme atopic dermatitis, and vulnerability to viral infections, prompted us to guage the potential for DOCK8 deficiency. Immunological assessments demonstrated decreased IgM, elevated IgE, T lymphocytepenia, particularly in CD4 T cells, decreased PHA blastogenesis some more intersting facts about the class is in Sainik school coaching in dehradun, and decreased CD27(+) CD19(+) reminiscence B cells. Western blotting revealed the absence of DOCK8 protein.

Investigation of genomic DNA by multiplex ligation-dependent probe amplification (MLPA) revealed a heterozygous massive deletion of 77 kb spanning from intron 5 to exon 22. DOCK8 cDNA sequencing revealed a nonsense mutation at place 740 (E740X). So far as we all know, that is the primary Japanese case of DOCK8 deficiency.

Recombinant Dedicator Of Cytokinesis 4 (DOCK4)

Dedicator of cytokinesis 8 (DOCK8) deficiency is an innate error of adaptive immunity characterised by recurrent infections with viruses, micro organism and fungi, very excessive serum IgE concentrations, and a progressive deterioration of T- and B-cell-mediated immunity.

DOCK1 Antibody

CSB-PA047488-
EUR 335
Description: A polyclonal antibody against DOCK1. Recognizes DOCK1 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000

DOCK1 Antibody

CSB-PA047488-100ul 100ul
EUR 316
Description: A polyclonal antibody against DOCK1. Recognizes DOCK1 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000

DOCK1 Antibody

1-CSB-PA101358
  • EUR 317.00
  • EUR 244.00
  • 100ul
  • 50ul
Description: A polyclonal antibody against DOCK1. Recognizes DOCK1 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:1000-1:2000, IHC:1:25-1:100

DOCK1 Antibody

1-CSB-PA619864LA01HU
  • EUR 317.00
  • EUR 335.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against DOCK1. Recognizes DOCK1 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200

DOCK1 Antibody

34642-100ul 100ul
EUR 252

DOCK1 Antibody

34642-50ul 50ul
EUR 187

DOCK1 Antibody

DF3984 200ul
EUR 304
Description: DOCK1 Antibody detects endogenous levels of total DOCK1.

DOCK1 Antibody

ABD3984 100 ug
EUR 438

DOCK1 antibody

70R-21517 50 ul
EUR 435
Description: Rabbit polyclonal DOCK1 antibody

DOCK1 antibody

70R-35827 100 ug
EUR 327
Description: Rabbit polyclonal DOCK1 antibody

DOCK1 antibody

70R-12505 100 ul
EUR 457
Description: Affinity purified Rabbit polyclonal DOCK1 antibody

Anti-DOCK1 antibody

STJ119485 100 µl
EUR 277
Description: This gene encodes a member of the dedicator of cytokinesis protein family. Dedicator of cytokinesis proteins act as guanine nucleotide exchange factors for small Rho family G proteins. The encoded protein regulates the small GTPase Rac, thereby influencing several biological processes, including phagocytosis and cell migration. Overexpression of this gene has also been associated with certain cancers. Alternative splicing results in multiple transcript variants.

Anti-DOCK1 antibody

STJ70065 100 µg
EUR 359

DOCK1 Conjugated Antibody

C34642 100ul
EUR 397

DOCK1 siRNA

20-abx914478
  • EUR 551.00
  • EUR 732.00
  • 15 nmol
  • 30 nmol

DOCK1 siRNA

20-abx914479
  • EUR 551.00
  • EUR 732.00
  • 15 nmol
  • 30 nmol

DOCK1 Peptide

45-489P 0.1 mg
EUR 338
Description: DOCK1 Peptide

DOCK1 Antibody, HRP conjugated

1-CSB-PA619864LB01HU
  • EUR 317.00
  • EUR 335.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against DOCK1. Recognizes DOCK1 from Human. This antibody is HRP conjugated. Tested in the following application: ELISA

DOCK1 Antibody, FITC conjugated

1-CSB-PA619864LC01HU
  • EUR 317.00
  • EUR 335.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against DOCK1. Recognizes DOCK1 from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

DOCK1 Antibody, Biotin conjugated

1-CSB-PA619864LD01HU
  • EUR 317.00
  • EUR 335.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against DOCK1. Recognizes DOCK1 from Human. This antibody is Biotin conjugated. Tested in the following application: ELISA

Human DOCK1 shRNA Plasmid

20-abx951246
  • EUR 801.00
  • EUR 1121.00
  • 150 µg
  • 300 µg

DOCK1 Rabbit pAb

A17359-100ul 100 ul
EUR 308

DOCK1 Rabbit pAb

A17359-200ul 200 ul
EUR 459

DOCK1 Rabbit pAb

A17359-20ul 20 ul
EUR 183

DOCK1 Rabbit pAb

A17359-50ul 50 ul
EUR 223

DOCK1 Blocking Peptide

DF3984-BP 1mg
EUR 195

Anti-DOCK1 (3D10)

YF-MA12721 100 ug
EUR 363
Description: Mouse monoclonal to DOCK1

Polyclonal Goat Anti-DOCK1 Antibody

AMM04959G 0.1 mg
EUR 484
Description: A polyclonal antibody raised in Goat that recognizes and binds to Human Goat Anti-DOCK1 . This antibody is tested and proven to work in the following applications:

DOCK1 ELISA Kit (Human) (OKCA01197)

OKCA01197 96 Wells
EUR 846
Description: Description of target: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Along with DOCK1, mediates CRK/CRKL regulation of epithelial and endothelial cell spreading and migration on type IV collagen (PubMed:19004829). Functions as a guanine nucleotide exchange factor (GEF), which activates Rac Rho small GTPases by exchanging bound GDP for free GTP. Its GEF activity may be enhanced by ELMO1 (PubMed:8657152).;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sanadwich ELISA;Sensitivity: 11.7 pg/mL

DOCK1 ORF Vector (Human) (pORF)

ORF018475 1.0 ug DNA
EUR 659

Mouse DOCK1 shRNA Plasmid

20-abx983627
  • EUR 801.00
  • EUR 1121.00
  • 150 µg
  • 300 µg

Dedicator of Cytokinesis 1 (DOCK1) Antibody

20-abx112009
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul

Dedicator of Cytokinesis 1 (DOCK1) Antibody

20-abx102732
  • EUR 425.00
  • EUR 133.00
  • EUR 1205.00
  • EUR 578.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Dedicator of Cytokinesis 1 (DOCK1) Antibody

abx147652-100ug 100 ug
EUR 439

Dedicator of Cytokinesis 1 (DOCK1) Antibody

20-abx014419
  • EUR 314.00
  • EUR 98.00
  • EUR 398.00
  • EUR 495.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

Dedicator of Cytokinesis 1 (DOCK1) Antibody

abx431929-200ul 200 ul
EUR 384

Dedicator Of Cytokinesis 1 (DOCK1) Antibody

20-abx211608
  • EUR 411.00
  • EUR 300.00
  • 100 ul
  • 50 ul

Dedicator Of Cytokinesis 1 (DOCK1) Antibody

abx330938-100ul 100 ul
EUR 425

Dedicator Of Cytokinesis 1 (DOCK1) Antibody

20-abx325559
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug

Dedicator Of Cytokinesis 1 (DOCK1) Antibody

20-abx333995
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

DOCK1 sgRNA CRISPR Lentivector set (Human)

K0623601 3 x 1.0 ug
EUR 339

Dedicator Of Cytokinesis 1 (DOCK1) Polyclonal Antibody (Human)

4-PAG175Hu01
  • EUR 247.00
  • EUR 2510.00
  • EUR 625.00
  • EUR 310.00
  • EUR 214.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Dedicator Of Cytokinesis 1 (DOCK1)

Dedicator Of Cytokinesis 1 (DOCK1) Antibody (HRP)

20-abx335295
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Leave a Reply

Your email address will not be published.